For example, it promotes the absorption of calcium and phosphorus from your gut ( 14).īut scientists have recently discovered that it also plays roles in other areas of health, such as immune function and protection against cancer ( 15). Vitamin D affects various cells related to bone health. This is similar to how most other steroid hormones work ( 12, 13). When the active form of vitamin D binds to this receptor, it turns genes on or off, leading to changes in your cells. This is the active, steroid-hormone form of vitamin D.Ĭalcitriol interacts with the vitamin D receptor (VDR), which is found in almost every single cell in your body ( 10, 11). Second, it is converted to calcitriol, or 1,25(OH)2D, mostly in your kidneys. Vitamin D needs to undergo two conversion steps to become active ( 8, 9).įirst, it is converted to calcidiol, or 25(OH)D, in your liver.
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